San Francisco CA is the most expensive location in the Americas as at January 2020. American countries and cities are extremely diverse ranging from the most developed, wealthy and technologically advanced, through to some of the poorest and least developed in the world, with a corresponding wide range in local cost of living.
https://www.xpatulator.com/cost-of-living-article/America-Expat-Cost-of-Living-Comparison_710.cfm
Expatriate International Cost of Living 